CBD & Fibromyalgia

Research for Fibromyalgia
General CBD research is in its infancy, so research on CBD for fibromyalgia could be considered embryonic. We just don’t have much to go on right now. A 2016 survey of the literature concluded that there’s not enough evidence to recommend any cannabis-based treatments for fibromyalgia or other rheumatic conditions.

However, this topic is likely to get a lot of future attention, for several reasons.

First, we have a pain epidemic in the U.S., and fibromyalgia is a major contributor to that. Current treatments just aren’t good enough for most of us, so there’s an enormous financial incentive to find something that’s better at relieving our pain and other symptoms.

Second, we have an opioid addiction and overdose epidemic in this country. Numerous studies have demonstrated that when a state legalizes marijuana, the number of opioid prescriptions drops. That’s good news for doctors looking for safer pain treatments, law enforcement agencies struggling to control the tide of illegal opioid use, and lawmakers looking for solutions to the opioid problem.

Third, CBD oil is believed to be effective against pain and inflammation, and, in its pure form, it’s generally regarded as safe.

Fourth, while anecdotal evidence certainly isn’t scientific proof of anything, we have an abundance of it from people with fibromyalgia who say CBD helps them, and you can bet that when patients who have hard-to-treat conditions tell their doctors something works, it piques their interest.

As for the scientific motivations behind further study, consider that CBD is believed to help relieve:

– Pain
– Insomnia
– Anxiety

When it comes to fibromyalgia symptoms, those three are significant.

A 2017 paper published in Expert Opinion on Therapeutic Targets suggested CBD as a possible way to diminish the activity of brain cells called glia, which leads to central sensitization. That’s a major feature of fibromyalgia and other central sensitivity syndromes such as chronic fatigue syndrome, irritable bowel syndrome, and migraine.

Fibromyalgia also involves something called endocannabinoid deficiency. That’s the system that deals with your body’s natural endocannabinoids as well as cannabis products that you may take in. That makes cannabis products a promising treatment.

A 2016 review published in Cannabis and Cannabinoid Research found evidence that CBD is effective in migraine and irritable bowel syndrome, which are related to fibromyalgia. It also stated that some cannabis-based treatments appeared effective for fibromyalgia. The authors stated that CBD is often preferable to patients due to the high and other effects associated with THC.

Several studies have suggested that CBD can fight inflammation. Fibromyalgia isn’t currently classified as an inflammatory condition, but research suggests that at least some cases may involve inflammation of a body-wide web of connective tissue called the fascia. If that’s accurate, it could be one more reason CBD should be considered.

SOURCE: https://www.verywellhealth.com/cbd-oil-for-fibromyalgia-4165993

CBD&FIBROMYALGIA

CBD & ADHD

ADHD or Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder, a syndrome of the brain that effects executive functioning skills, which includes important functions like attention, concentration, memory, impulsivity, and hyperactivity.

Some examples are wasting energy on trivial things, unable to complete tasks, inability to focus, easily distracted, and overthinking. Due to genetics, this disorder is caused by chemical and structural differences in the brain.

Some of the side effects associated with ADHD medications consist of:

Lack of sleep

Decreased Appetite

Delayed Growth

Headaches

Stomach Aches

Tics

Irritability

Changes in mood

If you have ADHD, taking control of your anxiety can be a huge step towards improving you ADHD and your daily life!

 

CBD&ADHD.pdf

CBD and PMS Pain

CBD oil – derived from cannabis plants – is gaining status around the world; but its pain-relieving, mood-boosting properties have serious research to back it up, and could help relieve period-related symptoms.

Cannabidiol, or CBD, is making headway in the natural health and wellness world, mainly due to the growing list of health benefits, including relief from PMS. It’s an active compound found in cannabis, but don’t let it’s association with marijuana scare you. You won’t get the mind-altering high because it contains little to none(0.03%) of the psychoactive component, THC (Tetrahydrocannabinol). Instead, the oil, which is extracted from the cannabis plant and mixed with carrier oils like almond, coconut, and olive, has been shown to help with pain relief. As a result, many women are turning to CBD specifically for PMS symptoms.

What’s more, it can be helpful treating cramps, too. CBD can be immensely helpful in treating the irritability and discomfort that comes during the premenstrual phase of our cycles. Because it has strong anti-inflammatory properties and is also a muscle relaxer, it can help with the overall tension, as well as menstrual cramps that can come later.

So how does it work? The body has its own endocannabinoid system (ECS) and internal cannabis receptors (the body’s internal cannabinoid system was named after the plant, which led to the discovery in the 1980s). There are cannabinoid receptors throughout the body – from the brain and central nervous system to the gut, connective tissues and nerves – and they work with the endocannabinoid system as a homeostatic regulator, meaning that the body is trying to maintain a state of balance in all its cells. In an indication of how that should actually feel, scientists named one of the key endocannabinoids ‘anandamide’ – the “Bliss Molecule”

How does CBD oil fit in to this? Well, interestingly, researchers have found that taking CBD oil promotes the body’s own internal cannabinoids to function more effectively – helping to reduce stress and inflammation within its own cells.

And whilst further research is needed into applications for women’s health specifically, scientists have found that those who suffer from endometriosis also have low levels of cannabinoid receptors, leading experts to suggest that CBD oil could offer relief from the condition.

All this comes with a note of caution that as yet the research into CBD is not complete; while there have been lots of anecdotal evidence around the use of CBD for PMS symptoms, and some preliminary research into pain relief, there have not yet been double-blind, placebo-controlled studies into the topic, and it’s important to check with your doctor, qualified nutritionist or herbal medicine practitioner first that CBD is right for you.

The current research, while not explicitly focused on PMS, certainly seems to suggest that if you’re looking for something natural and effective for your PMS tool belt, it’s worth a shot. Every day, there are more studies about the potential medical and daily wellness applications for CBD (and cannabis in general), whether to treat particular medical conditions or to help improve your emotional, physical, and mental health. Of course, these new studies are often confirming the anecdotal, lived experiences of many cannabis-savvy consumers.

CBD and Acid Reflux

Image result for cbd and acid reflux

 

Have you ever experienced heartburn after finishing a meal or eating spicy food? Have you ever felt heartburn or chest pain at all? Currently, 1 in 10 Americans experience GERD (Gastroesophageal Reflux Disease), which is most closely linked to the symptoms of heartburn. GERD and its symptoms, such as heartburn, can be painful and uncomfortable. Although pharmaceutical drugs are often used to treat GERD, cannabidiol is slowly emerging as a way to help treat this disease safely and effectively.

What is GERD?

Gastroesophageal Reflux Disease refers to the stomach and esophagus and the return of the contents back up to the esophagus. In normal digestion, the lower esophageal sphincter (LES) opens to allow food to pass into the stomach and closes to prevent food and stomach acid from flowing back into the esophagus. GERD, then, occurs when the LES is weak or inappropriately relaxes allowing the contents of the stomach to flow up into the esophagus. The “heartburn” is the discomfort experienced by the reflux of stomach content to the esophagus. Normally, the treatment is prescription medication or over-the-counter drugs. However, many prescriptions cause adverse side effects. Fortunately, CBD and cannabinoids can be used to combat GERD symptoms.

CBD Oil for GERD & Acid Reflux

Just as everybody has a lower esophageal sphincter, and potential to experience GERD, each body contains an endocannabinoid system (ECS). ECS has many known functions including memory, sensations, pain perception, anti-secretory effects, etc. One of the most particular symptoms that CBD helps to regulate is the secretion of gastric acids to the esophagus. By reacting with the endocannabinoid system, CBD has the power to greatly reduce the secretion of the acids that cause the actual burn when it comes to the heartburn symptoms of GERD. Beyond this, CBD and the ECS help to mitigate inflammation and mucosal damage in GERD, as well as lower esophageal relaxation, helping to prevent the severity of GERD, or stop it before effects begin to take place.

 

These are just a few examples of how CBD reacts to the gastric acid and intestinal secretions when it comes to GERD. CBD also has positive effects on other factors of the body that contribute to acid reflux and heartburn. CBD has the power to act as an anti-inflammatory to reduce esophageal discomfort and decreases the motility, or the ability for fluids to move around, in the esophagus and the gut which is the direct cause of the acid reflux. With decreased mobility and the reduction in inflammation, the main discomforting symptoms of GERD are treated.

 

If you experience heartburn, acid reflux, or GERD, try observing the foods you eat because they may be worsening GERD symptoms, especially caffeine and alcohol. However, above all else, CBD plays an essential role in treating GERD and its symptoms. If you’re interested in trying CBD, it’s suggested to consume it orally or sublingually with capsules or tinctures to prevent further irritation from occurring.

Source: https://kononaturals.com/cbd-oil-for-acid-reflux/

CBD and Cardiovascular Health

Image result for cbd and heart disease

Cannabinoids and Blood Pressure

Until recently, evidence has been (more or less) inconclusive, with findings going both ways. These studies, however, had been investigating cannabis flower with no control for strain, cannabinoid profile, or means of ingestion.

Different cannabinoids have different effects and attenuate the endocannabinoid system in different directions. It’s well known, for example, that THC and CBD have inverse effects to a degree.

Finally, one recent study, which specifically investigated whether CBD reduces blood pressure in human trials, put a rest to the controversy: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress.”

Cannabis and Cardiovascular Disease

These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial for cardiovascular diseases, especially in recovery from stroke and heart attack.

This study sheds light on one of the stickier areas within medical cannabis research: its effect on the cardiovascular system. Most investigations looking at long-term cannabis smokers find cardiovascular damage and attribute it to cannabis. Because this study utilized ingested CBD, they were able to separate the effects of smoking and the effects of the cannabinoid.

The negative effects, it turned out, were due more to the smoking than the cannabis itself.

How CBD Reduces Blood Pressure

Now, this is still a long way away from CBD being an effective treatment for cardiovascular diseases like hypertension. Serious conditions have many factors at play—lifestyle, diet, genetics, life circumstances, etc.—and taking some CBD oil isn’t necessarily going to make it all better. There are no magic pills to fix these things, despite what your friendly neighborhood pharmaceutical company would like you to believe.

While it may not be a cure for hypertension, cannabis does provide a natural, safe remedy for people to help manage their stress and blood pressure.

To minimize cardiovascular damage, you may want to consider an oral dose, through a CBD edible, tincture, or even pure CBD oil. However, if you’re set on smoking flower, reputable high CBD strains like Harlequin, Critical Mass, and Blue Shark may be helpful.

 

Source:https://haveaheartcc.com/can-cannabis-lower-blood-pressure/

CBD and Epilepsy/Seizures

 

There has been a lot of talk in the media about the use of cannabis products in the treatment of epilepsy and non-epileptic seizures. This has generated a lot of interest as well as confusion over the different forms of cannabis that are being discussed, their legality and their safety.

Medical cannabis has anticonvulsant properties. The cannabis plant contains 85 different chemical compounds called cannabinoids. The most commonly known is tetrahydrocannabinol (THC), but most of the anticonvulsant properties come from a cannabinoid called cannabidiol (CBD).Our cannabidiol products contain virtually no THC (0.3%).

The cannabidiol (CBD) has been shown to be very effective in the treatment of refractory epilepsy for some patients with Dravet and Lennox Gastaut syndromes, tuberous sclerosis and infantile spasms.

For many who have used CBD oil, the treatment has provided relief when nothing else could. About two thirds of epilepsy patients will be responsive to the first or second medicine given for epilepsy. However, once an epilepsy patient has taken two different medicines without relief, the odds that a third medication will work are less than 1 percent. That leaves other options, such as special diets, surgeries—or CBD oil!

CBD and Arthritis

Cannabidiol (CBD) is not psychoactive. One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol wont get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol CBD is inert.

  • CBD derived for the HEMP plant(male cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/bud producing plant) is currently still illegal in Canada. Technically speaking, it’s THC, the cannabinoid that gets you high, which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal amount of THC (0.3% or less per bottle/package).

Cannabinoids, such as CBD, attach themselves to specialized receptors in the brain and immune system. Researchers found that when CBD enters the body it can attach to CB2 receptors. Scientists believe CBD affects the way that these receptors respond to the signals that they recieve, helping reduce inflammation and pain. CB2 also plays a role in your immune system, attacking the tissue in your joints. This relationship tp the immune system could explain why CBD oil works well for Arthritis. In addition, CBD’s anti-inflammatory effects could also help slow down or stop the progression of RA/OA, which causes permanent damage to your joints over time. These effects also reduce several other inflammation-related RA/OA symptoms.

  • CBD relieves inflammation and joint pain
  • CBD slows the progression of joint damage
  • Cannabis-research firm, Brightfield Group, surveyed 2,400 users. This dramatic study found widespread satisfaction with CBD among regular consumers, and even revealed that 42% of those surveyed had given up pharmaceutical drugs in favour of CBD.
  • CBD oil helped reduce inflammatory pain in rats, highlighting that cannabinoid receptors are involved in joint nociception and may be advantages for the treatment of inflammatory pain.
  • A research review published in the European Journal of Neuroscience noted that increasing evidence from preclinical studies supports the therapeutic value of cannabinoids for osteoarthritis management.
  • A study published in the European Journal of Pain found that topical CBD application had therapeutic potential for relief of arthritis pain-related inflammation and behaviours.

 

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CBD: How It’s Made (CO2 Extraction)

Cannabidiol (CBD) is a non-psychoactive cannabinoid in the hemp plant which has a multitude of health benefits including its abilities to help mood, insomnia and sleep issues, stress, immune function, anxiety and depression, IBS, Parkinson’s, Multiple Sclerosis, ADHD, Fibromyalgia, and many more. In fact, the power of CBD oil is rapidly becoming undeniable due to its effects on the entire endocannabinoid system.

The CBD Extraction Process

There are several extraction methods which can be utilized to obtain cannabidiol from the hemp plant. The most common methods include the use of petroleum or naphtha, ethanol or carbon dioxide (CO2).

Petroleum and Naphtha CBD Extraction

Petroleum-based solvents focus on extracting THC and are considered a less expensive way to create a potent product. However, these solvents tend to produce lower concentrations of CBD and other non-psychoactive cannabinoids and terpenes. The petroleum extraction method is also considered unsafe because of the solvent residue that remains after extraction which could cause potential problems with your health.

Ethanol CBD Extraction

Ethanol-based extraction is a safer means to extract CBD oil; however, oil extracted with ethanol can have higher amounts of chlorophyll which can change the taste and colouring of the product. Furthermore, ethanol extraction methods prevent concentrating CBD levels. This means that larger amounts of oil should be consumed to obtain all health benefits.

CO2 Extraction Process

CO2 extraction is considered the best method to preserve CBD oil purity. This cannabinoid extraction process is the most expensive as it requires specialized equipment and training; however, unlike petroleum and ethanol methods, the CO2 technique is both non-toxic and produces a potent product, concentrated with high levels of CBD.

Organa Wellness Centre CBD oil is extracted using the CO2 method. Through this process, CO2 is pressurized and brought to a low temperature. This captures CO2 in a liquid state to be used as a safe and natural solvent, allowing the extraction of essential oils—like CBD and terpenes—from plant material, while eliminating THC and chlorophyll.

Processing CBD oil through this method is expensive; however, it is the safest, most effective way to create the highest quality of cannabinoids, terpenes, essential oils and other hemp plant compounds without residues.

 

 

CBD: Dosage Guide for Humans

The right dose can vary quite a bit from one situation to the next. Organa’s CBD hemp oil is used for anxiety, stress, arthritis, appetite, IBS, muscle spasms, seizures, neurological and digestive disorders, obsessions, past traumas, withdrawal, mood, Cancer, Diabetes, Chronic Pain, PTSD, Heart Disease, IDD, Autism, Anxiety, Depression, Mental Disorders, Parkinson’s, MS, Auto Immune Disorders, ADHD, Fibromyalgia, Eating Disorders, diabetes, antibiotic-resistant infections, alcoholism, SLEEP, Seizures, Strokes, memory and much more. During recovery from illness or surgery, CBD can stimulate the appetite and speed healing. Near the end of life, it can ease the pain and fear. CBD does all this by stimulating the endocannabinoid system. Everyone has different amounts of receptors so you may need to experiment to find the right amount and how often. Start with the recommended dose and expect to see results in 30 – 60 minutes, if not instantly. If there is no change after an hour, increase the dosage. For best results use daily.​

​To control pain, give every 8 hours or as needed. If pain relief is not effective a THC combination may be needed. For other uses, or to break unwanted behaviour patterns, give once or twice a day. ​

Cannabidiol (CBD) is Not Psychoactive  ​

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada.  This will change as of Oct. 17 2018, where everything will be legalized for recreational sales, as per current government plans.​

CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​

SHAKE BOTTLE REALLY WELL. START WITH 2-3 DROPS DIRECTLY UNDER THE TONGUE AND LET SIT 

FOR 30 SECONDS OR MORE.

1 FULL DROPPER = 10MG CBD

(50ML AND 30ML)

DETERMINING THE PERFECT DOSE FOR MAY REQUIRE SOME EXPERIMENTATION.

CBD & Multiple Sclerosis

Studies have shown cannabinoids are effective for managing symptoms associated with the disease and may also be beneficial for limiting the disease’s progression. Research findings suggest that cannabis could slow the neurodegenerative process of MS. Cannabinoids have shown they can modulate the inflammatory reaction and assist in neuro-regeneration. In one study, cannabinoids demonstrated neuroprotective effects during an animal model of multiple sclerosis, reducing the damage to myelin caused from inflammation. Another study found that cannabinoids administered to animals with a model of multiple sclerosis reduced neurological disability, improved motor coordination and limited the progression of the disease. ​

Cannabis can help multiple sclerosis patients manage the symptoms associated with their disease. Cannabis has shown to be effective at reducing pain, muscle stiffness and spasms, reduce inflammation. ​

A study done in 2011 showed CBD prevents immune cells attacking nerve cells in the spinal cords of mice with MS-like symptoms. The partially paralyzed limbs of the mice regained movement after they were injected with CBD. At first, mice responded by twitching their tails and then began walking without a limp. Research found much less inflammation in the spinal cords of mice treated with CBD than in untreated mice.​

Cannabidiol (CBD) is Not Psychoactive  ​

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol “CBD” is inert. ​

​CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​