Edibles: How Do They Work?

The primary psychoactive chemical in cannabis is THC, a cannabinoid. However, when these leaves are left raw and are un-aged, the cannabinoid found in them is THCA, which isn’t psychoactive at all. THCA only becomes THC — the stuff that gets you high — after it’s aged or, most effectively, exposed to heat. It’s a process called decarboxylation.

When looked at solely from the perspective of biochemical composition, raw cannabis leaves are excellent sources of certain vitamins, minerals and fiber. If that sounds surprising, keep in mind that even though they get you stoned, they are still green leafy plants. Raw cannabis is high in:

-Vitamin K (Essential for blood clotting) -Vitamin C (Essential for immune systems) -Iron (Essentialforbloodoxygenation) -Calcium (Essential for bones)

-Folate (Essential for DNA repair)
More specifically, cannabis is super high in fiber. So, if yourdietislacking,itcouldbethe answer.

Antioxidants are essential to our bodies because they protect us from stress and other damage, as well as against things like blood vessel disease and cancer. They’re also our body’s only defense against “free radicals,” which are highly reactive molecules that can wreak havoc on our bodies over time.

Cannabis, whether raw or cooked, is chockfull of antioxidants that our bodies need. So, whether you’re infusing weed into brownies or juicing raw leaves — you’re going to get the stuff you need.

Edibles aren’t particularly useful for sudden relief because they can take 90 minutes before they s tart having an effect, and unpredictable bouts of it. However, if you know when to anticipate them—for things like menstrual cramps, after chemotherapy, etc.—consuming marijuana is an excellent way to curb nausea, stomach pains and more.

People who ingest cannabis often experience a more intense and longer lasting full-body high than people who smoke it. You can experience a high that typically lasts one to two hours (while smoking). So, if you’re smoking medical marijuana for pain relief, cooking with it won’t just help locate and neutralize the pain you’re suffering from, but it’ll also provide more relief and for a longer duration of time.

A known fact is that you can’t really get all the benefits from smoking because it’s close to impossible to smoke a clinical level of the needed cannabinoids.However, when made into highly concentrated oils, you can get the recommended dosage in just a drop or two.

CBD and Depression

 Depression can be a predisposed condition (something you were born with) or brought on by an unfortunate event or trauma. Regardless of the cause, the symptoms of depression are often the same: feeling sad, loss of interest or pleasure in activities, changes in appetite, trouble sleeping, loss of energy, feeling worthless, and difficulty thinking, concentrating, or making decisions. ​

​ Two of the neurotransmitters affected during depression are serotonin and dopamine. Because levels of serotonin and dopamine are affected by things like diet, exercise, mental state, and stress levels, research supports the idea that some depressed people have reduced serotonin and dopamine transmission. This is where the use of CBD products can come into play.​

​ Unlike THC, the cannabinoid associated with causing marijuana’s “high effect,” CBD has a different, more indirect interaction with these cell receptors. At the same time, CBD has the unique ability to directly interact with other cell receptors, including serotonin and dopamine receptors. Thus, when ingested, CBD influences brain activity and one byproduct is the release of serotonin and dopamine throughout the body. ​

​ Research shows that CBD oil causes receptor 5-HT1A, which releases serotonin, to fire more effectively. This increases serotonin production and stabilizes its presence in the body. ​Low levels of serotonin production can lead to depression. Using CBD oil can result in the production of more serotonin to help ease this disease.​

CBD and Tourette Syndrome

 Tourette Syndrome (TS), or simply Tourette’s, is a relatively rare neurological disorder characterized by repetitive, involuntary movements and/or vocalizations. These movements and vocalizations are called tics. It is unknown exactly how many people suffer from Tourette’s, though studies suggest one out of every 162 children have the disorder. However, it’s estimated that roughly half of the children with Tourette’s are undiagnosed.​

​ While a number of medications are prescribed to those with TS, many come with several unwanted and potentially dangerous side effects. This has driven many people to search for alternative therapies to help fight the disorder and mitigate the symptoms. One of the most popular alternative therapies that has begun showing incredibly promising potential is CBD. ​

 Numerous studies have shown CBD may have the powerful ability to reduce the frequency and severity of tics and other TS symptoms. A case study of two patients with TS conducted in 2017 and published in the August issue of International Journal of Molecular Sciences found cannabinoids provided significant relief from vocal-blocking tics and were tolerated much better than commercial pharmaceuticals.​

​ It’s thought that cannabinoids are so beneficial to neurological disorders such as TS because of the numerous ECS receptors located in the brain. Because CB1 receptors primarily are found in the brain and nervous system, cannabinoids are able to directly impact the functioning of the nervous system and help to balance it out, thereby reducing tics.​

CBD and Skin Conditions

Balms, salves, and lotions made with CBD oil are used by thousands for all types of skin conditions, including daily skin care. Common Skin conditions include:​

    • Atopic dermatitis

 

    • Contact dermatitis

 

    • Rosacea

 

    • Psoriasis

 

    • Eczema

 

  • Chronic Pruritus

​ Of these skin conditions, there is one physiological process that seems to worsen them — inflammation.​ Although inflammation is our body’s natural defense against pathogens and irritants, this valuable defense can also turn against us, that’s where CBD comes into play. CBD is a powerful anti-inflammatory compound and the cannibanoid receptors play a role in modulating sensations like itching, pain, temperature and more.​

​ Topical CBD isn’t just for the skin conditions mentioned above. CBD’s anti-inflammatory and analgesic effects also work well for general pain caused by muscle injuries, joint pain caused by arthritis, and skin irritations. Topical CBD is also good for burns and infections, or simply healthier and younger looking skin.​

 Consult with a doctor to make sure you’re not allergic to Cannabis, and see if using topical CBD is right for you.​

CBD and PTSD

We all have natural Levels of anandamide,  This is the substance found naturally in your body that helps you “cope” emotionally. It relieves the effects of any stressful situation by temporarily putting you in a state of “bliss”.​

It has been determined that anandamide is at a considerably lower level in patients that are experiencing PTSD. It has also been known for a considerable amount of time that THC, which is a high percentage component of cannabis, has a built-in capacity to trigger the same receptors that are activated by anandamide.​

When experiencing PTSD, both CBD and THC can help you cope by putting you in that same “state of bliss” that is naturally created by anandamide. We can therefore safely assume that the utilization of Cannabis may be considered as a treatment against PTSD in order to deal with a shortage of anandamide.​

The consumption of CBD can have a drastic impact on the reduction of anxiety among people who are suffering from PTSD. A huge benefit of using CBD is that CBD doesn’t have any psychoactive action, so it can be used daily at work or while driving. CBD helps treat PTSD in a very different manner to THC. Indeed, PTSD patients all have far lower levels of endocannabinoids, along with higher CB1 receptor densities. Normally, the CB1 receptor deactivates any traumatic memories you may have so you basically ‘forget.’ If you have an endocannabinoid deficiency, on the other hand, you will suffer from chronic anxiety, impaired fear distinction, and other issues associated with PTSD. Cannabinoids act on the two receptors, CB1 and CB2, and helps them regain normal function.​

Benefits of CBD For Horses

 

CBD FOR HORSES

CBD oil for horses enables them to benefit from the natural healing powers of cannabis without being exposed to THC.

CBD has become an increasingly popular therapy for horses, especially those who are prone to joint problems, lameness, and anxiety. Independent trials conducted by Equine Veterinarians suggested that horses who were treated with CBD oil enjoyed detectable health benefits, including reduced anxiety, improved mobility, and reduced pain. It’s very common for horses to experience inflammation and pain in their joints. The weight of the body puts a strain on the connective tissue and the joints, and if you have a horse who is very active or they have a working role, this can further increase the risk of swelling and discomfort. CBD for horses can provide relief for general aches and pains, arthritis and joint stiffness.

Horses can endure scary, unnerving experiences and this can contribute to anxiety. If your horse is anxious about traveling or they don’t like to be contained, CBD oil can reduce stress and make them feel calm and more content, your horse will seem happier, and hopefully, they’ll continue to be their fun and playful selves.

If you are considering giving your horse CBD, it’s important to get the dosage right. A general guideline would be up to 25mg per day to boost general health, up to 80 mg per day to ease anxiety and 100-200mg per day to alleviate chronic pain. Optimum dosages will depend on the height and weight of the horse. It’s always best to start with a small dose and increase it gradually.

Indica, Sativa and Hybrid Strains: What is the difference?

 

  There are over 1000 different strains of cannabis that have evolved over that last several decades with constant new developments thanks to the wonderful breeders trying to increase the quality and targeting specific issues someone may have. These strains are commonly divided into 3 main categories: Sativa, Indica and Hybrids. It is important for someone using cannabis for medical purposes to know the difference between them to better treat or help with symptoms of specific ailments or conditions.

  Let’s start with Cannabis Sativa. Sativa strains generally originate in the equatorial regions for example: Thailand, Southern India, Jamaica and Mexico to name a few. The Sativa plants grow to be quite large in size, about 8-15 feet, and they require more light and do take longer to grow and mature compared to the Indica plant. Commonly the colour of the plant are a lighter shade of green, with buds growing along the length of the branches. Typically the buds weigh less than the Indica due to lower density, and normally take anywhere from 60-90 days to fully flower. The leaves on the Sativa plant are long and thin and contain lower CBD and higher THC amounts. Sativas are know to give the feelings of being “High” or having a head high. It is considered to give increased energy, productivity, and alertness. Sativas are helpful with treating Anxiety and Depression, Chronic pain, ADHD, HIV/AIDS, Glaucoma, Alzheimer’s Disease, Mood swings, Stress Relief, Concentration, Creativity and increases Serotonin. Typically a Sativa is consumed during the day.

  Next let’s talk about Cannabis Indica. Most varieties or strains of Indica come from Central Asia and the Indian Subcontinent like Afghanistan, Pakistan, Northern India, Tibet, Nepal and so on. Indica plants are smaller in size, about 2-6 feet in height and bush like. The leaves are wide and thick and contain higher CBD and lower THC that the Sativa. The buds are dense and heavily fragrant, growing in clusters around the nodes of the stems and branches with short spaces in between clusters. The Indica plant is deeper in colour and typically takes 45-60 days to fully flower which is much sooner than the Sativa. The Indica strain is know for the feeling of being “Stoned” or giving a full body high, which is why this strain is considered a night time Cannabis. This strain helps with  treatments of Cancer, Multiple Sclerosis, Fibromyalgia, Lupus, Sleep Apnea, Parkinson’s, Arthritis, Crohn’s Disease, PMS, Epilepsy, Inflammation, Anxiety disorders including OCD, PTSD and Panic Disorders, Insomnia, Nausea, Physical and Mental pain, and Headaches. It increases relaxation and dopamine making it easier to fall asleep and stay asleep and help increases appetite.

  Hybrid plants are a combination of two different strains of cannabis that theoretically possess the most beneficial medical properties of both strains. Normally breeders cross two strains in an attempt to deliver the best possible benefits to specific needs. Breeders can choose to combine Indica and Sativa together, or two Indicas and 2 Sativas together. When a strain displayed the name Indica Dominant or Sativa  Dominant, it means the Hybrid contains contains more of one parents traits than the other. The look and traits of the plant are all dependant on the strains combined.  Often the strains are labeled with a sativa/indica ratio like 60/40 Sat/Ind, other times only a percentage eg. 70% Indica and 80% SativaSativa Dominant Hybrids give a cerebral high with relaxing body effects along with the medical and mental relief. Even Hybrids are the ideal strain for people seeking a perfect blend between body and head high.  Indica Dominant Hybrid provide a full body pain relief with relaxing head high. Recommended for night time to sleep or day time for minor pain. It is a great choice for people suffering from autoimmune diseases and depression.

Cannabis Ruderalis is another species of cannabis whose potential benefits have only begun to be explored. This species of cannabis grows wild in parts of Eastern Europe and Russia, so it is accustomed to colder weather. Ruderalis plants contain lower percentages of THC, but are frequently cross-bred with Sativa strains to produce plants that grow short like Ruderalis, and can bear the weather of outdoor grows up north where Sativa strains can not usually flourish. These Hybrids are known as auto-flowering strains, because of the short flowering period that Ruderalis carries with it 2-3 weeks after germination. The strains are typically more resistant to insect infestation and disease pressures, and are thought to have high CBD content. The whole life span of these plants can be as short as 7 weeks long, and are relatively simple to grow, which has made them more popular among home growers.

How THC Works In The Body

 

THC (Tetrahydrocannabinol) is a chemical compound found in cannabis that gives you the feeling of being “high”. There are multiple different strains of cannabis, and each one will give you a different sensation or feeling.

THC has many medical benefits such as: PTSD, Neuropathic and Chronic pain, Insomnia, Nausea, Inflammation, Arthritis, Migraines, Cancer, Crohn’s Disease, Multiple Sclerosis, Glaucoma, Alzheimer’s Disease, Fibromyalgia, ADHD, Sleep Apnea, and Appetite loss to name a few.

There are many different ways of taking THC products, like edibles, tinctures, and even topical treatments, however the most common way is to smoke it. Vaporizers heat cannabis to vaporize its active ingredients without burning, which makes an inhalable alternative to smoking. When cannabis is ingested, it enters the stomach and the blood there absorbs it. It then travels to the liver and from there to the rest of the body. THC is absorbed slower this way in comparison to smoking, the levels of THC are lower however the effects last longer. When cannabis is inhaled, it goes directly into your lungs where it is absorbed into your bloodstream which goes to your brain and then to the rest of your body. It is the quickest way to get the THC into your bloodstream.

The purpose of your lungs are to take in oxygen and remove carbon dioxide as a waste product, this process is called “gas exchange”. Lungs are a pair of spongy air filled organs located on either side of your chest or thorax. The windpipe, or trachea, conducts air that has been inhaled into the lungs through it tubular branches called bronchi. The bronchi is divided into smaller and smaller bronchioles that finally become microscopic. The air then travels the the Alveoli. These alveoli line the lungs by the millions, this is where the “gas exchange” happens. The surface area of the alveoli is greater than the skin which makes it easy for THC to enter the bloodstream. Lungs absorb smoke within seconds of it being inhaled.

The brain tells your systems to resist foreign substances, but since cannabinoids have a place in the brains working, it allows them to enter. THC typically reaches the brain seconds after inhalation and begins to work right away. Neurons are the cells that process information in the brain. Chemicals called neurotransmitters allow neurons to communicate with each other, they fill the gap, or synapse between two neurons and bind to protein receptors which allows areas in the body and brain to be turned off. Some neurons have thousands of receptors that are specific to particular neurotransmitters. Chemicals like THC, can copy or block actions of neurotransmitters and interfere with normal functions. Short-term memory, coordination, learning and problem solving are all areas of which your brain’s cannabinoid receptors can affect both physically and mentally. Anandamide are neurotransmitters that activate the cannabinoid receptors. Like THC, anandamide is a cannabinoid, however its one your body makes. THC copy’s actions of the cannabinoid receptors and activates neurons which causes effects on the body and mind

 When THC binds to the receptors, it leads to deep relaxation reducing nerve pain and muscle spasms , reduced pain and inflammation, and boosts your appetite. THC can cause some side effects including sedation, dizziness, dry mouth, short term memory loss and increased heart rate. Anxiety and paranoia are commonly reported however when THC and CBD are consumed together, These side effects are much smaller or not experienced at all.

CBD and ADHD

    ADHD stands for Attention Deficit Hyperactivity Disorder, and is a neurodevelopmental disorder, a syndrome of the brain that affects executive functioning skills which includes important functions like attention, concentration, memory, motivation and effort, learning from mistakes, impulsivity, hyperactivity, organization and social skills to name a few. Some examples are wasting energy on things that really don’t matter, unable to complete important tasks because they are unable to focus, jumping from one shiny object to the next, increased anxiety, and overthinking things. Due to genetics, this disorder is caused by chemical and structural differences in the brain.

   Treatment for ADHD is most commonly a combination of medication and Behaviour Therapy. Behaviour Therapy can teach people coping skills and strategies, learn how to focus, and how to change or redirect their line of thinking.  Learned behaviours can overcome some of the symptoms of ADHD, and most adults can function without medication. Some of the side effects associated with ADHD medications consist of :

  • Sleeping problems
  • Decreased appetite
  • Delayed growth (children)
  • Headaches
  • Stomachaches
  • Rebound irritability when medication wears off
  • Tics
  • Moodyness
  • Irritability

 If you have ADHD, taking control of your anxiety can be a huge step towards improving your ADHD. CBD oil can boost your mental clarity and can help the way you feel on any given day. Some people have noticed after taking CBD effects from taking it happen instantaneously, they had less mental resistance, improved communication with other people and being more talkative, feelings of living in their body and not living in their head, nerves were calmed, no brain fog, feel more connected to others, important tasks were being completed as opposed to being side tracked and less irritability towards other people and themselves.