CBD and Cardiovascular Health

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Cannabinoids and Blood Pressure

Until recently, evidence has been (more or less) inconclusive, with findings going both ways. These studies, however, had been investigating cannabis flower with no control for strain, cannabinoid profile, or means of ingestion.

Different cannabinoids have different effects and attenuate the endocannabinoid system in different directions. It’s well known, for example, that THC and CBD have inverse effects to a degree.

Finally, one recent study, which specifically investigated whether CBD reduces blood pressure in human trials, put a rest to the controversy: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress.”

Cannabis and Cardiovascular Disease

These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial for cardiovascular diseases, especially in recovery from stroke and heart attack.

This study sheds light on one of the stickier areas within medical cannabis research: its effect on the cardiovascular system. Most investigations looking at long-term cannabis smokers find cardiovascular damage and attribute it to cannabis. Because this study utilized ingested CBD, they were able to separate the effects of smoking and the effects of the cannabinoid.

The negative effects, it turned out, were due more to the smoking than the cannabis itself.

How CBD Reduces Blood Pressure

Now, this is still a long way away from CBD being an effective treatment for cardiovascular diseases like hypertension. Serious conditions have many factors at play—lifestyle, diet, genetics, life circumstances, etc.—and taking some CBD oil isn’t necessarily going to make it all better. There are no magic pills to fix these things, despite what your friendly neighborhood pharmaceutical company would like you to believe.

While it may not be a cure for hypertension, cannabis does provide a natural, safe remedy for people to help manage their stress and blood pressure.

To minimize cardiovascular damage, you may want to consider an oral dose, through a CBD edible, tincture, or even pure CBD oil. However, if you’re set on smoking flower, reputable high CBD strains like Harlequin, Critical Mass, and Blue Shark may be helpful.

Source:https://haveaheartcc.com/can-cannabis-lower-blood-pressure/

CBD and Epilepsy/Seizures

 

There has been a lot of talk in the media about the use of cannabis products in the treatment of epilepsy and non-epileptic seizures. This has generated a lot of interest as well as confusion over the different forms of cannabis that are being discussed, their legality and their safety.

Medical cannabis has anticonvulsant properties. The cannabis plant contains 85 different chemical compounds called cannabinoids. The most commonly known is tetrahydrocannabinol (THC), but most of the anticonvulsant properties come from a cannabinoid called cannabidiol (CBD).Our cannabidiol products contain virtually no THC (0.3%).

The cannabidiol (CBD) has been shown to be very effective in the treatment of refractory epilepsy for some patients with Dravet and Lennox Gastaut syndromes, tuberous sclerosis and infantile spasms.

For many who have used CBD oil, the treatment has provided relief when nothing else could. About two thirds of epilepsy patients will be responsive to the first or second medicine given for epilepsy. However, once an epilepsy patient has taken two different medicines without relief, the odds that a third medication will work are less than 1 percent. That leaves other options, such as special diets, surgeries—or CBD oil!

CBD: How It’s Made (CO2 Extraction)

Cannabidiol (CBD) is a non-psychoactive cannabinoid in the hemp plant which has a multitude of health benefits including its abilities to help mood, insomnia and sleep issues, stress, immune function, anxiety and depression, IBS, Parkinson’s, Multiple Sclerosis, ADHD, Fibromyalgia, and many more. In fact, the power of CBD oil is rapidly becoming undeniable due to its effects on the entire endocannabinoid system.

The CBD Extraction Process

There are several extraction methods which can be utilized to obtain cannabidiol from the hemp plant. The most common methods include the use of petroleum or naphtha, ethanol or carbon dioxide (CO2).

Petroleum and Naphtha CBD Extraction

Petroleum-based solvents focus on extracting THC and are considered a less expensive way to create a potent product. However, these solvents tend to produce lower concentrations of CBD and other non-psychoactive cannabinoids and terpenes. The petroleum extraction method is also considered unsafe because of the solvent residue that remains after extraction which could cause potential problems with your health.

Ethanol CBD Extraction

Ethanol-based extraction is a safer means to extract CBD oil; however, oil extracted with ethanol can have higher amounts of chlorophyll which can change the taste and colouring of the product. Furthermore, ethanol extraction methods prevent concentrating CBD levels. This means that larger amounts of oil should be consumed to obtain all health benefits.

CO2 Extraction Process

CO2 extraction is considered the best method to preserve CBD oil purity. This cannabinoid extraction process is the most expensive as it requires specialized equipment and training; however, unlike petroleum and ethanol methods, the CO2 technique is both non-toxic and produces a potent product, concentrated with high levels of CBD.

Organa Wellness Centre CBD oil is extracted using the CO2 method. Through this process, CO2 is pressurized and brought to a low temperature. This captures CO2 in a liquid state to be used as a safe and natural solvent, allowing the extraction of essential oils—like CBD and terpenes—from plant material, while eliminating THC and chlorophyll.

Processing CBD oil through this method is expensive; however, it is the safest, most effective way to create the highest quality of cannabinoids, terpenes, essential oils and other hemp plant compounds without residues.

 

 

CBD: Dosage Guide for Humans

The right dose can vary quite a bit from one situation to the next. Organa’s CBD hemp oil is used for anxiety, stress, arthritis, appetite, IBS, muscle spasms, seizures, neurological and digestive disorders, obsessions, past traumas, withdrawal, mood, Cancer, Diabetes, Chronic Pain, PTSD, Heart Disease, IDD, Autism, Anxiety, Depression, Mental Disorders, Parkinson’s, MS, Auto Immune Disorders, ADHD, Fibromyalgia, Eating Disorders, diabetes, antibiotic-resistant infections, alcoholism, SLEEP, Seizures, Strokes, memory and much more. During recovery from illness or surgery, CBD can stimulate the appetite and speed healing. Near the end of life, it can ease the pain and fear. CBD does all this by stimulating the endocannabinoid system. Everyone has different amounts of receptors so you may need to experiment to find the right amount and how often. Start with the recommended dose and expect to see results in 30 – 60 minutes, if not instantly. If there is no change after an hour, increase the dosage. For best results use daily.​

​To control pain, give every 8 hours or as needed. If pain relief is not effective a THC combination may be needed. For other uses, or to break unwanted behaviour patterns, give once or twice a day. ​

Cannabidiol (CBD) is Not Psychoactive  ​

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada.  This will change as of Oct. 17 2018, where everything will be legalized for recreational sales, as per current government plans.​

CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​

SHAKE BOTTLE REALLY WELL. START WITH 2-3 DROPS DIRECTLY UNDER THE TONGUE AND LET SIT 

FOR 30 SECONDS OR MORE.

1 FULL DROPPER = 10MG CBD

(50ML AND 30ML)

DETERMINING THE PERFECT DOSE FOR MAY REQUIRE SOME EXPERIMENTATION.

 

CBD & Multiple Sclerosis

Studies have shown cannabinoids are effective for managing symptoms associated with the disease and may also be beneficial for limiting the disease’s progression. Research findings suggest that cannabis could slow the neurodegenerative process of MS. Cannabinoids have shown they can modulate the inflammatory reaction and assist in neuro-regeneration. In one study, cannabinoids demonstrated neuroprotective effects during an animal model of multiple sclerosis, reducing the damage to myelin caused from inflammation. Another study found that cannabinoids administered to animals with a model of multiple sclerosis reduced neurological disability, improved motor coordination and limited the progression of the disease. ​

Cannabis can help multiple sclerosis patients manage the symptoms associated with their disease. Cannabis has shown to be effective at reducing pain, muscle stiffness and spasms, reduce inflammation. ​

A study done in 2011 showed CBD prevents immune cells attacking nerve cells in the spinal cords of mice with MS-like symptoms. The partially paralyzed limbs of the mice regained movement after they were injected with CBD. At first, mice responded by twitching their tails and then began walking without a limp. Research found much less inflammation in the spinal cords of mice treated with CBD than in untreated mice.​

Cannabidiol (CBD) is Not Psychoactive  ​

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol “CBD” is inert. ​

​CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​

 

 

CBD and How It Helps Pain

According to one study posted to Neurotherapeutics, this is because CBD itself does very little to the ECS. Instead, it activates or inhibits other compounds in the endocannabinoid system.​

For instance, CBD stops the body from the degradation of anandamide, one compound associated with regulating pain. Increased levels of anandamide in the bloodstream may reduce the amount of pain a person feels.​

Various levels and combinations of cannabinoids, terpenoids and flavonoids provide many benefits to the human body, dilating blood vessels, stimulating bone growth, protecting damaged brain cells, killing certain kinds of cancer cells, preventing seizure, controlling muscle spasticity, killing viruses and bacteria to name a few. It is the combination of varying levels of cannabinoids, terpenoids and flavonoids that seem to make the most effective medicine for specific symptoms and dis-eases – the isolated components appear to be less effective but nonetheless still therapeutic.​

Cannabis has been found to ease general pain, chemo induced neuropathy, and nausea, as well as increase appetite and reverse wasting. It is also effective in controlling muscles spasms and seizures, healing damaged brain cells, protecting against the ravages of Alzheimer’s, and is an effective antioxidant.​

Cannabidiol (CBD) is Not Psychoactive

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol “CBD” is inert. ​

​CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​

Edibles: How Do They Work?

The primary psychoactive chemical in cannabis is THC, a cannabinoid. However, when these leaves are left raw and are un-aged, the cannabinoid found in them is THCA, which isn’t psychoactive at all. THCA only becomes THC — the stuff that gets you high — after it’s aged or, most effectively, exposed to heat. It’s a process called decarboxylation.

When looked at solely from the perspective of biochemical composition, raw cannabis leaves are excellent sources of certain vitamins, minerals and fiber. If that sounds surprising, keep in mind that even though they get you stoned, they are still green leafy plants. Raw cannabis is high in:

-Vitamin K (Essential for blood clotting) -Vitamin C (Essential for immune systems) -Iron (Essentialforbloodoxygenation) -Calcium (Essential for bones)

-Folate (Essential for DNA repair)
More specifically, cannabis is super high in fiber. So, if yourdietislacking,itcouldbethe answer.

Antioxidants are essential to our bodies because they protect us from stress and other damage, as well as against things like blood vessel disease and cancer. They’re also our body’s only defense against “free radicals,” which are highly reactive molecules that can wreak havoc on our bodies over time.

Cannabis, whether raw or cooked, is chockfull of antioxidants that our bodies need. So, whether you’re infusing weed into brownies or juicing raw leaves — you’re going to get the stuff you need.

Edibles aren’t particularly useful for sudden relief because they can take 90 minutes before they s tart having an effect, and unpredictable bouts of it. However, if you know when to anticipate them—for things like menstrual cramps, after chemotherapy, etc.—consuming marijuana is an excellent way to curb nausea, stomach pains and more.

People who ingest cannabis often experience a more intense and longer lasting full-body high than people who smoke it. You can experience a high that typically lasts one to two hours (while smoking). So, if you’re smoking medical marijuana for pain relief, cooking with it won’t just help locate and neutralize the pain you’re suffering from, but it’ll also provide more relief and for a longer duration of time.

A known fact is that you can’t really get all the benefits from smoking because it’s close to impossible to smoke a clinical level of the needed cannabinoids.However, when made into highly concentrated oils, you can get the recommended dosage in just a drop or two.

CBD and Depression

 Depression can be a predisposed condition (something you were born with) or brought on by an unfortunate event or trauma. Regardless of the cause, the symptoms of depression are often the same: feeling sad, loss of interest or pleasure in activities, changes in appetite, trouble sleeping, loss of energy, feeling worthless, and difficulty thinking, concentrating, or making decisions. ​

​ Two of the neurotransmitters affected during depression are serotonin and dopamine. Because levels of serotonin and dopamine are affected by things like diet, exercise, mental state, and stress levels, research supports the idea that some depressed people have reduced serotonin and dopamine transmission. This is where the use of CBD products can come into play.​

​ Unlike THC, the cannabinoid associated with causing marijuana’s “high effect,” CBD has a different, more indirect interaction with these cell receptors. At the same time, CBD has the unique ability to directly interact with other cell receptors, including serotonin and dopamine receptors. Thus, when ingested, CBD influences brain activity and one byproduct is the release of serotonin and dopamine throughout the body. ​

​ Research shows that CBD oil causes receptor 5-HT1A, which releases serotonin, to fire more effectively. This increases serotonin production and stabilizes its presence in the body. ​Low levels of serotonin production can lead to depression. Using CBD oil can result in the production of more serotonin to help ease this disease.​

CBD and Tourette Syndrome

 Tourette Syndrome (TS), or simply Tourette’s, is a relatively rare neurological disorder characterized by repetitive, involuntary movements and/or vocalizations. These movements and vocalizations are called tics. It is unknown exactly how many people suffer from Tourette’s, though studies suggest one out of every 162 children have the disorder. However, it’s estimated that roughly half of the children with Tourette’s are undiagnosed.​

​ While a number of medications are prescribed to those with TS, many come with several unwanted and potentially dangerous side effects. This has driven many people to search for alternative therapies to help fight the disorder and mitigate the symptoms. One of the most popular alternative therapies that has begun showing incredibly promising potential is CBD. ​

 Numerous studies have shown CBD may have the powerful ability to reduce the frequency and severity of tics and other TS symptoms. A case study of two patients with TS conducted in 2017 and published in the August issue of International Journal of Molecular Sciences found cannabinoids provided significant relief from vocal-blocking tics and were tolerated much better than commercial pharmaceuticals.​

​ It’s thought that cannabinoids are so beneficial to neurological disorders such as TS because of the numerous ECS receptors located in the brain. Because CB1 receptors primarily are found in the brain and nervous system, cannabinoids are able to directly impact the functioning of the nervous system and help to balance it out, thereby reducing tics.​

CBD and Skin Conditions

Balms, salves, and lotions made with CBD oil are used by thousands for all types of skin conditions, including daily skin care. Common Skin conditions include:​

    • Atopic dermatitis

    • Contact dermatitis

    • Rosacea

    • Psoriasis

    • Eczema

  • Chronic Pruritus

​ Of these skin conditions, there is one physiological process that seems to worsen them — inflammation.​ Although inflammation is our body’s natural defense against pathogens and irritants, this valuable defense can also turn against us, that’s where CBD comes into play. CBD is a powerful anti-inflammatory compound and the cannibanoid receptors play a role in modulating sensations like itching, pain, temperature and more.​

​ Topical CBD isn’t just for the skin conditions mentioned above. CBD’s anti-inflammatory and analgesic effects also work well for general pain caused by muscle injuries, joint pain caused by arthritis, and skin irritations. Topical CBD is also good for burns and infections, or simply healthier and younger looking skin.​

 Consult with a doctor to make sure you’re not allergic to Cannabis, and see if using topical CBD is right for you.​