CBD+THC and the Herpes Simplex Virus

The Herpes Simplex Virus(HSV) is a widespread virus that can cause ailments such as cold sores, genital herpes, chickenpox and mono. Studies have shown 50%-90% of the population carry either HSV 1 or HSV 2 and as of today it remains incurable. HSV is a retrovirus which means it is able to lay dormant in your body without detection from your immune system. It does this by inserting itself into your DNA. Even though there is no permanent cure, there are ways to suppress the unpleasant symptoms. Symptoms include; swollen lymph nodes, flu like symptoms, headaches, blisters, inflammation, redness, cracked skin, itching and pain.

CBD can help with ALL of these symptoms. CBD is known to be a natural anti-inflammatory. A study by the London school of Pharmacology showed CBD has great capability to fend off foreign pathogens in the body. Applying CBD topically to sores will help decrease redness, itching, pain and cracking skin. Ingesting CBD through tincture, capsule or edible is also beneficial to HSV symptoms, helping with pain, enlarged lymph nodes, headaches and also just getting rid of the general blah feeling that comes with an outbreak.

THC does not suppress the detectable symptoms of HSV but since the first study by the University of South Florida in 1991 many more studies have confirmed that THC lowered the ability of the virus to cause an outbreak by 80%. THC inhibits HSV by targeting the ORF50 protein which is essential for HSV to come out of its dormant state. So while THC does not decrease symptoms during an outbreak, regular use can drastically decrease the frequency of outbreaks.

CBD & Eating Disorders (Anorexia)

According to the Association for Anorexia Nervosa and Associated Disorders (ANAD), a staggering 30 million people across the U.S. suffer from an eating disorder. This statistic applies to all ages, race, and genders, although it is mostly seen in females.

The statistics surrounding anorexia from there do not get any better, and in fact, they are pretty horrifying, with eating disorders holding the highest mortality rates of any other mental illness, it stands to reason that people are now looking to potential alternative treatments for the disease.

CBD can help to treat the worst symptoms of anorexia without causing toxicity, or any other feelings of loss of control that can come with marijuana.

The researchers discovered that CB1 agonists – the scientific term to describe anything that helps trigger the receptor – possess orexigenic effects, which enhance appetite as well as increasing the actual rewarding value of food. It’s important to remember that a person suffering from anorexia doesn’t just not want to eat food, but they lose the positive association we have when we eat food that nourishes us.

When it comes down to it, both CBD and cannabis as a whole can be incredibly effective treatments for anorexia and other eating disorders. However, that being said there are many areas where CBD comes out on top, from psychoactive THC through to affordability and efficacy in the treatment of symptoms.

**THC while being used to combat many of the side effects of anorexia can have a detrimental impact on anxiety, if the individual is already suffering. While it can ease anxiety and depression, it can also make matters worse.**

CBD & Arthritis

Cannabidiol (CBD) is not psychoactive. One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol wont get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol CBD is inert.

  • CBD derived for the HEMP plant(male cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/bud producing plant) is currently still illegal in Canada. Technically speaking, it’s THC, the cannabinoid that gets you high, which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal amount of THC (0.3% or less per bottle/package).

Cannabinoids, such as CBD, attach themselves to specialized receptors in the brain and immune system. Researchers found that when CBD enters the body it can attach to CB2 receptors. Scientists believe CBD affects the way that these receptors respond to the signals that they recieve, helping reduce inflammation and pain. CB2 also plays a role in your immune system, attacking the tissue in your joints. This relationship tp the immune system could explain why CBD oil works well for Arthritis. In addition, CBD’s anti-inflammatory effects could also help slow down or stop the progression of RA/OA, which causes permanent damage to your joints over time. These effects also reduce several other inflammation-related RA/OA symptoms.

  • CBD relieves inflammation and joint pain
  • CBD slows the progression of joint damage
  • Cannabis-research firm, Brightfield Group, surveyed 2,400 users. This dramatic study found widespread satisfaction with CBD among regular consumers, and even revealed that 42% of those surveyed had given up pharmaceutical drugs in favour of CBD.
  • CBD oil helped reduce inflammatory pain in rats, highlighting that cannabinoid receptors are involved in joint nociception and may be advantages for the treatment of inflammatory pain.
  • A research review published in the European Journal of Neuroscience noted that increasing evidence from preclinical studies supports the therapeutic value of cannabinoids for osteoarthritis management.
  • A study published in the European Journal of Pain found that topical CBD application had therapeutic potential for relief of arthritis pain-related inflammation and behaviours.

 

BEST PRODUCTS FOR ARTHRITIS:

ORGANA CBD INFUSED SALVE

ORGANA CBD INFUSED HUMAN TINCTURE

CBD & Fibromyalgia

Research for Fibromyalgia
General CBD research is in its infancy, so research on CBD for fibromyalgia could be considered embryonic. We just don’t have much to go on right now. A 2016 survey of the literature concluded that there’s not enough evidence to recommend any cannabis-based treatments for fibromyalgia or other rheumatic conditions.

However, this topic is likely to get a lot of future attention, for several reasons.

First, we have a pain epidemic in the U.S., and fibromyalgia is a major contributor to that. Current treatments just aren’t good enough for most of us, so there’s an enormous financial incentive to find something that’s better at relieving our pain and other symptoms.

Second, we have an opioid addiction and overdose epidemic in this country. Numerous studies have demonstrated that when a state legalizes marijuana, the number of opioid prescriptions drops. That’s good news for doctors looking for safer pain treatments, law enforcement agencies struggling to control the tide of illegal opioid use, and lawmakers looking for solutions to the opioid problem.

Third, CBD oil is believed to be effective against pain and inflammation, and, in its pure form, it’s generally regarded as safe.

Fourth, while anecdotal evidence certainly isn’t scientific proof of anything, we have an abundance of it from people with fibromyalgia who say CBD helps them, and you can bet that when patients who have hard-to-treat conditions tell their doctors something works, it piques their interest.

As for the scientific motivations behind further study, consider that CBD is believed to help relieve:

– Pain
– Insomnia
– Anxiety

When it comes to fibromyalgia symptoms, those three are significant.

A 2017 paper published in Expert Opinion on Therapeutic Targets suggested CBD as a possible way to diminish the activity of brain cells called glia, which leads to central sensitization. That’s a major feature of fibromyalgia and other central sensitivity syndromes such as chronic fatigue syndrome, irritable bowel syndrome, and migraine.

Fibromyalgia also involves something called endocannabinoid deficiency. That’s the system that deals with your body’s natural endocannabinoids as well as cannabis products that you may take in. That makes cannabis products a promising treatment.

A 2016 review published in Cannabis and Cannabinoid Research found evidence that CBD is effective in migraine and irritable bowel syndrome, which are related to fibromyalgia. It also stated that some cannabis-based treatments appeared effective for fibromyalgia. The authors stated that CBD is often preferable to patients due to the high and other effects associated with THC.

Several studies have suggested that CBD can fight inflammation. Fibromyalgia isn’t currently classified as an inflammatory condition, but research suggests that at least some cases may involve inflammation of a body-wide web of connective tissue called the fascia. If that’s accurate, it could be one more reason CBD should be considered.

SOURCE: https://www.verywellhealth.com/cbd-oil-for-fibromyalgia-4165993

 

CBD and Acid Reflux

Image result for cbd and acid reflux

 

Have you ever experienced heartburn after finishing a meal or eating spicy food? Have you ever felt heartburn or chest pain at all? Currently, 1 in 10 Americans experience GERD (Gastroesophageal Reflux Disease), which is most closely linked to the symptoms of heartburn. GERD and its symptoms, such as heartburn, can be painful and uncomfortable. Although pharmaceutical drugs are often used to treat GERD, cannabidiol is slowly emerging as a way to help treat this disease safely and effectively.

What is GERD?

Gastroesophageal Reflux Disease refers to the stomach and esophagus and the return of the contents back up to the esophagus. In normal digestion, the lower esophageal sphincter (LES) opens to allow food to pass into the stomach and closes to prevent food and stomach acid from flowing back into the esophagus. GERD, then, occurs when the LES is weak or inappropriately relaxes allowing the contents of the stomach to flow up into the esophagus. The “heartburn” is the discomfort experienced by the reflux of stomach content to the esophagus. Normally, the treatment is prescription medication or over-the-counter drugs. However, many prescriptions cause adverse side effects. Fortunately, CBD and cannabinoids can be used to combat GERD symptoms.

CBD Oil for GERD & Acid Reflux

Just as everybody has a lower esophageal sphincter, and potential to experience GERD, each body contains an endocannabinoid system (ECS). ECS has many known functions including memory, sensations, pain perception, anti-secretory effects, etc. One of the most particular symptoms that CBD helps to regulate is the secretion of gastric acids to the esophagus. By reacting with the endocannabinoid system, CBD has the power to greatly reduce the secretion of the acids that cause the actual burn when it comes to the heartburn symptoms of GERD. Beyond this, CBD and the ECS help to mitigate inflammation and mucosal damage in GERD, as well as lower esophageal relaxation, helping to prevent the severity of GERD, or stop it before effects begin to take place.

 

These are just a few examples of how CBD reacts to the gastric acid and intestinal secretions when it comes to GERD. CBD also has positive effects on other factors of the body that contribute to acid reflux and heartburn. CBD has the power to act as an anti-inflammatory to reduce esophageal discomfort and decreases the motility, or the ability for fluids to move around, in the esophagus and the gut which is the direct cause of the acid reflux. With decreased mobility and the reduction in inflammation, the main discomforting symptoms of GERD are treated.

 

If you experience heartburn, acid reflux, or GERD, try observing the foods you eat because they may be worsening GERD symptoms, especially caffeine and alcohol. However, above all else, CBD plays an essential role in treating GERD and its symptoms. If you’re interested in trying CBD, it’s suggested to consume it orally or sublingually with capsules or tinctures to prevent further irritation from occurring.

Source: https://kononaturals.com/cbd-oil-for-acid-reflux/

CBD and Cardiovascular Health

Image result for cbd and heart disease

Cannabinoids and Blood Pressure

Until recently, evidence has been (more or less) inconclusive, with findings going both ways. These studies, however, had been investigating cannabis flower with no control for strain, cannabinoid profile, or means of ingestion.

Different cannabinoids have different effects and attenuate the endocannabinoid system in different directions. It’s well known, for example, that THC and CBD have inverse effects to a degree.

Finally, one recent study, which specifically investigated whether CBD reduces blood pressure in human trials, put a rest to the controversy: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress.”

Cannabis and Cardiovascular Disease

These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial for cardiovascular diseases, especially in recovery from stroke and heart attack.

This study sheds light on one of the stickier areas within medical cannabis research: its effect on the cardiovascular system. Most investigations looking at long-term cannabis smokers find cardiovascular damage and attribute it to cannabis. Because this study utilized ingested CBD, they were able to separate the effects of smoking and the effects of the cannabinoid.

The negative effects, it turned out, were due more to the smoking than the cannabis itself.

How CBD Reduces Blood Pressure

Now, this is still a long way away from CBD being an effective treatment for cardiovascular diseases like hypertension. Serious conditions have many factors at play—lifestyle, diet, genetics, life circumstances, etc.—and taking some CBD oil isn’t necessarily going to make it all better. There are no magic pills to fix these things, despite what your friendly neighborhood pharmaceutical company would like you to believe.

While it may not be a cure for hypertension, cannabis does provide a natural, safe remedy for people to help manage their stress and blood pressure.

To minimize cardiovascular damage, you may want to consider an oral dose, through a CBD edible, tincture, or even pure CBD oil. However, if you’re set on smoking flower, reputable high CBD strains like Harlequin, Critical Mass, and Blue Shark may be helpful.

Source:https://haveaheartcc.com/can-cannabis-lower-blood-pressure/

CBD & Multiple Sclerosis

Studies have shown cannabinoids are effective for managing symptoms associated with the disease and may also be beneficial for limiting the disease’s progression. Research findings suggest that cannabis could slow the neurodegenerative process of MS. Cannabinoids have shown they can modulate the inflammatory reaction and assist in neuro-regeneration. In one study, cannabinoids demonstrated neuroprotective effects during an animal model of multiple sclerosis, reducing the damage to myelin caused from inflammation. Another study found that cannabinoids administered to animals with a model of multiple sclerosis reduced neurological disability, improved motor coordination and limited the progression of the disease. ​

Cannabis can help multiple sclerosis patients manage the symptoms associated with their disease. Cannabis has shown to be effective at reducing pain, muscle stiffness and spasms, reduce inflammation. ​

A study done in 2011 showed CBD prevents immune cells attacking nerve cells in the spinal cords of mice with MS-like symptoms. The partially paralyzed limbs of the mice regained movement after they were injected with CBD. At first, mice responded by twitching their tails and then began walking without a limp. Research found much less inflammation in the spinal cords of mice treated with CBD than in untreated mice.​

Cannabidiol (CBD) is Not Psychoactive  ​

One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol won’t get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol “CBD” is inert. ​

​CBD derived from the HEMP plant (the male Cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/ bud producing plant) is currently still illegal in Canada. Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal limit of THC .3% or less per bottle/ package. ​

 

 

CBD and Skin Conditions

Balms, salves, and lotions made with CBD oil are used by thousands for all types of skin conditions, including daily skin care. Common Skin conditions include:​

    • Atopic dermatitis

    • Contact dermatitis

    • Rosacea

    • Psoriasis

    • Eczema

  • Chronic Pruritus

​ Of these skin conditions, there is one physiological process that seems to worsen them — inflammation.​ Although inflammation is our body’s natural defense against pathogens and irritants, this valuable defense can also turn against us, that’s where CBD comes into play. CBD is a powerful anti-inflammatory compound and the cannibanoid receptors play a role in modulating sensations like itching, pain, temperature and more.​

​ Topical CBD isn’t just for the skin conditions mentioned above. CBD’s anti-inflammatory and analgesic effects also work well for general pain caused by muscle injuries, joint pain caused by arthritis, and skin irritations. Topical CBD is also good for burns and infections, or simply healthier and younger looking skin.​

 Consult with a doctor to make sure you’re not allergic to Cannabis, and see if using topical CBD is right for you.​

How CBD and THC Can Help With Your Arthritis

 

  Arthritis affects 1 in 5 Canadians everyday. The two most common kind of arthritis are:

Rheumatoid arthritis (RA): a disease where a persons body attacks their joints, causing inflammation. it commonly affects the hands and feet amd leads to painful, swollen and stiff joints

Osteoarthritis (OA): a degenerative disease that affects joint, cartilage and bones causing paint and stiffness, most commonly in the hips, knees and thumb joints.

  CBD affects your immune system, which naturally makes it helpful for an autoimmune conditions like RA. Studies published in the Journal Rheumatology from DR. Sheng-Ming Dai of China’s Second Military Medical University found that CB2 receptors are found in unusually high levels in the joint tissue or arthritis patients. The use of cannabis is shown to fight inflammation in the joints by activating the pathways of the CB2 receptors.

  But it’s not just CBD that can lend a helping hand. “Chronic pain is a symptom of rheumatoid arthritis, and when it comes to chronic pain, we have 9,000 patient years of data showing that THC [the active ingredient in cannabis] effectively treats it,” says Jahan Marcu, PhD, the Chief Scientific Officer for Americans for Safe Access, an organization devoted to the legalization of cannabis for therapeutic use. “Cannabinoids stop the transmission of pain and decrease inflammation, and that’s very important for people with joint issues.” On a basic level, THC is anti-inflammatory and analgesic (it kills pain), and it’s also known to reduce the anxiety and depression that goes with diseases (especially ailments that are cause a loss of mobility like rheumatoid arthritis). Have you ever read about how smoking weed can cause seizure patients to relax? Based on similar physiological principles, people with chronic pain and stiff joints may find that their body naturally loosens when using marijuana.

  Essentially, all of these scientific studies support one of the key principles of medicinal marijuana: that both non-psychoactive CBD and psychoactive THC work wonders for those suffering from joint pain.

  People have been using marijuana as a source of pain relief for thousands of years. Gooey Rabinski, an aptly named author considering he writes about that sweet Mary-Jane, writes, “Until the dawn of the 20th century, pot—albeit in tincture form, not smoked—was the primary form of pain killer in the United States. One hundred years ago, if a young girl skinned her knee, she was given a marijuana tincture, not an orange and white Bayer aspirin.”

  THC is omnipresent, but CBD has been historically more difficult to come across. However, in the contemporary golden age of cannabis culture, CBD is readily available to be vaped, smoked, applied topically, or taken as a tincture.

  One thing’s for sure: for those suffering from chronic pain in their joints, a little bit of chronic can go a long way. Give CBD a shot, you might love the effects. We rely on CBD after every ski day, backpacking trip, and workout—there’s just nothing better from a natural pain relief and relaxation standpoint.

CBD and Heart Disease

  CBD relaxes the arterial walls of the Heart. Studies have shown that CBD helps in relaxing the arterial walls. This relieves tension within the blood vessels. Relaxing the arterial walls protects arteries against inflammation. CBD has been proven effective as a way of reducing metabolic issues of increased glucose responses that are present in most heart disease sufferers. That’s because it decreases the permeability of the arterial wall.

  Heart Disease can cause inflammation- CBD can relieve that. There is a lot of inflammation in heart disease patients. New studies show that the anti-inflammatory and immune modulating abilities of CBD coupled with its antioxidant effects provide protection to the heart against tissue damage, This damage occurs when the condition leads to lack of blood and oxygen supply. Additionally, CBD provides protection to the heart against cardiomyopathy. This is a condition that causes thickening and hardening as well as eventual limitation of blood flow. Studies have shown that CBD stops the production of endotoxin. These are pro-inflammatory cytokines that cause progression of the heart condition. As such, by inhibiting their production, CBD helps in the therapeutic aid of the heart disease.

  CBD Could Help With Arterial Plaque Reduction.  Arterial plaque is usually a significant factor of heart disease. Thats because once plaque builds up on the arterial walls, it hinders the heart from pumping blood properly. CBD has been proven effective in decreasing plaque adhesion on the arterial walls. This is very important since the heart disease progresses when the plaque continues to build up on the arterial wall.