CBD and Cardiovascular Health

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Cannabinoids and Blood Pressure

Until recently, evidence has been (more or less) inconclusive, with findings going both ways. These studies, however, had been investigating cannabis flower with no control for strain, cannabinoid profile, or means of ingestion.

Different cannabinoids have different effects and attenuate the endocannabinoid system in different directions. It’s well known, for example, that THC and CBD have inverse effects to a degree.

Finally, one recent study, which specifically investigated whether CBD reduces blood pressure in human trials, put a rest to the controversy: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress.”

Cannabis and Cardiovascular Disease

These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial for cardiovascular diseases, especially in recovery from stroke and heart attack.

This study sheds light on one of the stickier areas within medical cannabis research: its effect on the cardiovascular system. Most investigations looking at long-term cannabis smokers find cardiovascular damage and attribute it to cannabis. Because this study utilized ingested CBD, they were able to separate the effects of smoking and the effects of the cannabinoid.

The negative effects, it turned out, were due more to the smoking than the cannabis itself.

How CBD Reduces Blood Pressure

Now, this is still a long way away from CBD being an effective treatment for cardiovascular diseases like hypertension. Serious conditions have many factors at play—lifestyle, diet, genetics, life circumstances, etc.—and taking some CBD oil isn’t necessarily going to make it all better. There are no magic pills to fix these things, despite what your friendly neighborhood pharmaceutical company would like you to believe.

While it may not be a cure for hypertension, cannabis does provide a natural, safe remedy for people to help manage their stress and blood pressure.

To minimize cardiovascular damage, you may want to consider an oral dose, through a CBD edible, tincture, or even pure CBD oil. However, if you’re set on smoking flower, reputable high CBD strains like Harlequin, Critical Mass, and Blue Shark may be helpful.

 

Source:https://haveaheartcc.com/can-cannabis-lower-blood-pressure/

Edibles: How Do They Work?

The primary psychoactive chemical in cannabis is THC, a cannabinoid. However, when these leaves are left raw and are un-aged, the cannabinoid found in them is THCA, which isn’t psychoactive at all. THCA only becomes THC — the stuff that gets you high — after it’s aged or, most effectively, exposed to heat. It’s a process called decarboxylation.

When looked at solely from the perspective of biochemical composition, raw cannabis leaves are excellent sources of certain vitamins, minerals and fiber. If that sounds surprising, keep in mind that even though they get you stoned, they are still green leafy plants. Raw cannabis is high in:

-Vitamin K (Essential for blood clotting) -Vitamin C (Essential for immune systems) -Iron (Essentialforbloodoxygenation) -Calcium (Essential for bones)

-Folate (Essential for DNA repair)
More specifically, cannabis is super high in fiber. So, if yourdietislacking,itcouldbethe answer.

Antioxidants are essential to our bodies because they protect us from stress and other damage, as well as against things like blood vessel disease and cancer. They’re also our body’s only defense against “free radicals,” which are highly reactive molecules that can wreak havoc on our bodies over time.

Cannabis, whether raw or cooked, is chockfull of antioxidants that our bodies need. So, whether you’re infusing weed into brownies or juicing raw leaves — you’re going to get the stuff you need.

Edibles aren’t particularly useful for sudden relief because they can take 90 minutes before they s tart having an effect, and unpredictable bouts of it. However, if you know when to anticipate them—for things like menstrual cramps, after chemotherapy, etc.—consuming marijuana is an excellent way to curb nausea, stomach pains and more.

People who ingest cannabis often experience a more intense and longer lasting full-body high than people who smoke it. You can experience a high that typically lasts one to two hours (while smoking). So, if you’re smoking medical marijuana for pain relief, cooking with it won’t just help locate and neutralize the pain you’re suffering from, but it’ll also provide more relief and for a longer duration of time.

A known fact is that you can’t really get all the benefits from smoking because it’s close to impossible to smoke a clinical level of the needed cannabinoids.However, when made into highly concentrated oils, you can get the recommended dosage in just a drop or two.

CBD and Tourette Syndrome

 Tourette Syndrome (TS), or simply Tourette’s, is a relatively rare neurological disorder characterized by repetitive, involuntary movements and/or vocalizations. These movements and vocalizations are called tics. It is unknown exactly how many people suffer from Tourette’s, though studies suggest one out of every 162 children have the disorder. However, it’s estimated that roughly half of the children with Tourette’s are undiagnosed.​

​ While a number of medications are prescribed to those with TS, many come with several unwanted and potentially dangerous side effects. This has driven many people to search for alternative therapies to help fight the disorder and mitigate the symptoms. One of the most popular alternative therapies that has begun showing incredibly promising potential is CBD. ​

 Numerous studies have shown CBD may have the powerful ability to reduce the frequency and severity of tics and other TS symptoms. A case study of two patients with TS conducted in 2017 and published in the August issue of International Journal of Molecular Sciences found cannabinoids provided significant relief from vocal-blocking tics and were tolerated much better than commercial pharmaceuticals.​

​ It’s thought that cannabinoids are so beneficial to neurological disorders such as TS because of the numerous ECS receptors located in the brain. Because CB1 receptors primarily are found in the brain and nervous system, cannabinoids are able to directly impact the functioning of the nervous system and help to balance it out, thereby reducing tics.​

Indica, Sativa and Hybrid Strains: What is the difference?

 

  There are over 1000 different strains of cannabis that have evolved over that last several decades with constant new developments thanks to the wonderful breeders trying to increase the quality and targeting specific issues someone may have. These strains are commonly divided into 3 main categories: Sativa, Indica and Hybrids. It is important for someone using cannabis for medical purposes to know the difference between them to better treat or help with symptoms of specific ailments or conditions.

  Let’s start with Cannabis Sativa. Sativa strains generally originate in the equatorial regions for example: Thailand, Southern India, Jamaica and Mexico to name a few. The Sativa plants grow to be quite large in size, about 8-15 feet, and they require more light and do take longer to grow and mature compared to the Indica plant. Commonly the colour of the plant are a lighter shade of green, with buds growing along the length of the branches. Typically the buds weigh less than the Indica due to lower density, and normally take anywhere from 60-90 days to fully flower. The leaves on the Sativa plant are long and thin and contain lower CBD and higher THC amounts. Sativas are know to give the feelings of being “High” or having a head high. It is considered to give increased energy, productivity, and alertness. Sativas are helpful with treating Anxiety and Depression, Chronic pain, ADHD, HIV/AIDS, Glaucoma, Alzheimer’s Disease, Mood swings, Stress Relief, Concentration, Creativity and increases Serotonin. Typically a Sativa is consumed during the day.

  Next let’s talk about Cannabis Indica. Most varieties or strains of Indica come from Central Asia and the Indian Subcontinent like Afghanistan, Pakistan, Northern India, Tibet, Nepal and so on. Indica plants are smaller in size, about 2-6 feet in height and bush like. The leaves are wide and thick and contain higher CBD and lower THC that the Sativa. The buds are dense and heavily fragrant, growing in clusters around the nodes of the stems and branches with short spaces in between clusters. The Indica plant is deeper in colour and typically takes 45-60 days to fully flower which is much sooner than the Sativa. The Indica strain is know for the feeling of being “Stoned” or giving a full body high, which is why this strain is considered a night time Cannabis. This strain helps with  treatments of Cancer, Multiple Sclerosis, Fibromyalgia, Lupus, Sleep Apnea, Parkinson’s, Arthritis, Crohn’s Disease, PMS, Epilepsy, Inflammation, Anxiety disorders including OCD, PTSD and Panic Disorders, Insomnia, Nausea, Physical and Mental pain, and Headaches. It increases relaxation and dopamine making it easier to fall asleep and stay asleep and help increases appetite.

  Hybrid plants are a combination of two different strains of cannabis that theoretically possess the most beneficial medical properties of both strains. Normally breeders cross two strains in an attempt to deliver the best possible benefits to specific needs. Breeders can choose to combine Indica and Sativa together, or two Indicas and 2 Sativas together. When a strain displayed the name Indica Dominant or Sativa  Dominant, it means the Hybrid contains contains more of one parents traits than the other. The look and traits of the plant are all dependant on the strains combined.  Often the strains are labeled with a sativa/indica ratio like 60/40 Sat/Ind, other times only a percentage eg. 70% Indica and 80% SativaSativa Dominant Hybrids give a cerebral high with relaxing body effects along with the medical and mental relief. Even Hybrids are the ideal strain for people seeking a perfect blend between body and head high.  Indica Dominant Hybrid provide a full body pain relief with relaxing head high. Recommended for night time to sleep or day time for minor pain. It is a great choice for people suffering from autoimmune diseases and depression.

Cannabis Ruderalis is another species of cannabis whose potential benefits have only begun to be explored. This species of cannabis grows wild in parts of Eastern Europe and Russia, so it is accustomed to colder weather. Ruderalis plants contain lower percentages of THC, but are frequently cross-bred with Sativa strains to produce plants that grow short like Ruderalis, and can bear the weather of outdoor grows up north where Sativa strains can not usually flourish. These Hybrids are known as auto-flowering strains, because of the short flowering period that Ruderalis carries with it 2-3 weeks after germination. The strains are typically more resistant to insect infestation and disease pressures, and are thought to have high CBD content. The whole life span of these plants can be as short as 7 weeks long, and are relatively simple to grow, which has made them more popular among home growers.

How THC Works In The Body

 

THC (Tetrahydrocannabinol) is a chemical compound found in cannabis that gives you the feeling of being “high”. There are multiple different strains of cannabis, and each one will give you a different sensation or feeling.

THC has many medical benefits such as: PTSD, Neuropathic and Chronic pain, Insomnia, Nausea, Inflammation, Arthritis, Migraines, Cancer, Crohn’s Disease, Multiple Sclerosis, Glaucoma, Alzheimer’s Disease, Fibromyalgia, ADHD, Sleep Apnea, and Appetite loss to name a few.

There are many different ways of taking THC products, like edibles, tinctures, and even topical treatments, however the most common way is to smoke it. Vaporizers heat cannabis to vaporize its active ingredients without burning, which makes an inhalable alternative to smoking. When cannabis is ingested, it enters the stomach and the blood there absorbs it. It then travels to the liver and from there to the rest of the body. THC is absorbed slower this way in comparison to smoking, the levels of THC are lower however the effects last longer. When cannabis is inhaled, it goes directly into your lungs where it is absorbed into your bloodstream which goes to your brain and then to the rest of your body. It is the quickest way to get the THC into your bloodstream.

The purpose of your lungs are to take in oxygen and remove carbon dioxide as a waste product, this process is called “gas exchange”. Lungs are a pair of spongy air filled organs located on either side of your chest or thorax. The windpipe, or trachea, conducts air that has been inhaled into the lungs through it tubular branches called bronchi. The bronchi is divided into smaller and smaller bronchioles that finally become microscopic. The air then travels the the Alveoli. These alveoli line the lungs by the millions, this is where the “gas exchange” happens. The surface area of the alveoli is greater than the skin which makes it easy for THC to enter the bloodstream. Lungs absorb smoke within seconds of it being inhaled.

The brain tells your systems to resist foreign substances, but since cannabinoids have a place in the brains working, it allows them to enter. THC typically reaches the brain seconds after inhalation and begins to work right away. Neurons are the cells that process information in the brain. Chemicals called neurotransmitters allow neurons to communicate with each other, they fill the gap, or synapse between two neurons and bind to protein receptors which allows areas in the body and brain to be turned off. Some neurons have thousands of receptors that are specific to particular neurotransmitters. Chemicals like THC, can copy or block actions of neurotransmitters and interfere with normal functions. Short-term memory, coordination, learning and problem solving are all areas of which your brain’s cannabinoid receptors can affect both physically and mentally. Anandamide are neurotransmitters that activate the cannabinoid receptors. Like THC, anandamide is a cannabinoid, however its one your body makes. THC copy’s actions of the cannabinoid receptors and activates neurons which causes effects on the body and mind

 When THC binds to the receptors, it leads to deep relaxation reducing nerve pain and muscle spasms , reduced pain and inflammation, and boosts your appetite. THC can cause some side effects including sedation, dizziness, dry mouth, short term memory loss and increased heart rate. Anxiety and paranoia are commonly reported however when THC and CBD are consumed together, These side effects are much smaller or not experienced at all.

Hemp Seed Oil vs CBD Oil

  Hemp seed oil and CBD oil are similar in some ways however there are some important differences. First lets take a look at what they are and how to distinguish the two.

 What is Hemp seed oil? Hemp seed oil is extracted from the seed of the hemp plant, the seeds contain as much as 50%of their weight in oil. While it can be extracted from all of the plants in the cannabis family, industrial hemp is the only plant this oil is made from, this kind of hemp is specifically produced industrially and the amount of psychoactive substances contained are minimal.

 Hemp seed oil is used for making things like lotions and soaps and is a great moisturizer for after the shower. It can be used as a base for different forms of plastic instead of using petroleum and can even be used in the production of eco-friendly paints compared to petroleum based paints. Hemp oil is amazing to use in cooking, it can give a nice nutty and crispy taste to your food like in a salad or can be used to replace other vegetable oils.

 What is CBD oil? CBD is one of the most vital components of marijuana. CBD, otherwise known as Cannabidiol, is the natural component of both hemp or cannabis. CBD oil is cannabis oil that has a significant content of cannabidiol and is made from flower, leaves and stalks of the plant, not from the seed. The extraction methods vary, but the safest known process is the oil based method, where the plant is soaked in a carrier oil- typically hemp or olive- to separate the components. Contrast this with the unsafe solvent-based approach that pushes butane, hexane or alcohol through the plant to extract the chemicals. Larger better funded operations may also opt to use a CO2-based approach which places the material under high pressure. This method offers the safest alternative and produces the purest end product.

  CBD is used most in the medical marijuana industry to help various conditions without the typical intoxicating effects of marijuana. CBD can be used for the treatment of cancer, inflammation, anxiety, depression, chronic pain, seizures, neurodegenerative disorders and so much more. CBD can be put into many things to get results for example soaps, lotions, salves, tinctures, food and candy, shampoos and capsules to name a few, depending on the issue you are trying to treat.

  Hemp and Marijuana are cousins in the plant world but marijuana has a much higher THC content than hemp. Hemp contains low levels of CBD– typically less than 25 parts per million, while CBD oil can have up to 15 percent CBD. Unlike CBD, Hemp has a strong nutritional value, as it is high in polyunsaturated fats like Omega-6 and Omega-3 as well as Vitamin E.

 

Differences between THC and CBD

      

Tetrahydrocannabinol (THC) and Cannabidoil (CBD) are two types of cannabinoids found naturally in the resin of the marijuana plant, Cannabis sativa. Both of these substances interact with the cannabinoid receptors found in the human body, but the effects brought on by these compounds couldn’t be more opposite. For this reason, CBD is used more often for medical treatments then THC. THC is found in the cannabis plant which is a flower plant of three species, Sativa, Indica and Ruderalis. CBD is found in both cannabis and hemp plants. The hemp plant only shows traces of THC, small traces of THC is needed to activate the CBD oil in your body.

  CBD has the same chemical formula as THC however the atoms are arranged slightly different. This slight difference caused the THC to create a psychoactive affect, While CBD lacks that as an influence. CBD accounts for up to 40%of cannabis extracts. Its plentiful nature, coupled with its failure to produce a “High” effect, make it a strong running mate for medical proposes. Some effects of CBD can be a decrease in anxiety and a decrease in inflammation, relief from convolutions and nausea, and a reduction of psychoactive symptoms. Studies have shown CBD can help with lowering feelings of depression and social anxiety, side effects of cancer treatment like nausea and increased appetite and reducing psychotic symptoms that come with Schizophrenia.

  THC is the main psychoactive component of the marijuana plant, or the primary agent responsible for creating the feeling of being “high”. This compound works by imitating the effects of anandamide, a neurotransmitter produced naturally by the human body to help modulate sleeping and eating habits as well as the perception of pain. Effects of THC can be the feeling of relaxation, fatigue, reduced aggression, hunger, and the altered sense of sight, smell and hearing. Research shows that THC may help in the treatment of Multiple Sclerosis by improving spasticity and bladder function while reducing spasms and central pain, alleviates symptoms and stimulates appetite and eating.

  Taking CBD and THC both topically and internally is a healthy, natural and safe way to reduce the toxic load of chemicals you are putting into your body. Your body absorbs everything you put on your skin and what you ingest. Take a second next time you put on A535, for example- after the gym for pain, and read the ingredients. The chemicals absorb into your liver which can actually cause liver failure. Nobody wants to live with pain of any kind. Here at Organa we want to make sure you have the right educated information in choosing the best THC and CBD products, to help you get through your day to day activities without pumping your body full of pain medications. Simply call or email us with any questions you may have.