CBD and Acid Reflux

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Have you ever experienced heartburn after finishing a meal or eating spicy food? Have you ever felt heartburn or chest pain at all? Currently, 1 in 10 Americans experience GERD (Gastroesophageal Reflux Disease), which is most closely linked to the symptoms of heartburn. GERD and its symptoms, such as heartburn, can be painful and uncomfortable. Although pharmaceutical drugs are often used to treat GERD, cannabidiol is slowly emerging as a way to help treat this disease safely and effectively.

What is GERD?

Gastroesophageal Reflux Disease refers to the stomach and esophagus and the return of the contents back up to the esophagus. In normal digestion, the lower esophageal sphincter (LES) opens to allow food to pass into the stomach and closes to prevent food and stomach acid from flowing back into the esophagus. GERD, then, occurs when the LES is weak or inappropriately relaxes allowing the contents of the stomach to flow up into the esophagus. The “heartburn” is the discomfort experienced by the reflux of stomach content to the esophagus. Normally, the treatment is prescription medication or over-the-counter drugs. However, many prescriptions cause adverse side effects. Fortunately, CBD and cannabinoids can be used to combat GERD symptoms.

CBD Oil for GERD & Acid Reflux

Just as everybody has a lower esophageal sphincter, and potential to experience GERD, each body contains an endocannabinoid system (ECS). ECS has many known functions including memory, sensations, pain perception, anti-secretory effects, etc. One of the most particular symptoms that CBD helps to regulate is the secretion of gastric acids to the esophagus. By reacting with the endocannabinoid system, CBD has the power to greatly reduce the secretion of the acids that cause the actual burn when it comes to the heartburn symptoms of GERD. Beyond this, CBD and the ECS help to mitigate inflammation and mucosal damage in GERD, as well as lower esophageal relaxation, helping to prevent the severity of GERD, or stop it before effects begin to take place.

 

These are just a few examples of how CBD reacts to the gastric acid and intestinal secretions when it comes to GERD. CBD also has positive effects on other factors of the body that contribute to acid reflux and heartburn. CBD has the power to act as an anti-inflammatory to reduce esophageal discomfort and decreases the motility, or the ability for fluids to move around, in the esophagus and the gut which is the direct cause of the acid reflux. With decreased mobility and the reduction in inflammation, the main discomforting symptoms of GERD are treated.

 

If you experience heartburn, acid reflux, or GERD, try observing the foods you eat because they may be worsening GERD symptoms, especially caffeine and alcohol. However, above all else, CBD plays an essential role in treating GERD and its symptoms. If you’re interested in trying CBD, it’s suggested to consume it orally or sublingually with capsules or tinctures to prevent further irritation from occurring.

Source: https://kononaturals.com/cbd-oil-for-acid-reflux/

CBD and Cardiovascular Health

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Cannabinoids and Blood Pressure

Until recently, evidence has been (more or less) inconclusive, with findings going both ways. These studies, however, had been investigating cannabis flower with no control for strain, cannabinoid profile, or means of ingestion.

Different cannabinoids have different effects and attenuate the endocannabinoid system in different directions. It’s well known, for example, that THC and CBD have inverse effects to a degree.

Finally, one recent study, which specifically investigated whether CBD reduces blood pressure in human trials, put a rest to the controversy: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress.”

Cannabis and Cardiovascular Disease

These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial for cardiovascular diseases, especially in recovery from stroke and heart attack.

This study sheds light on one of the stickier areas within medical cannabis research: its effect on the cardiovascular system. Most investigations looking at long-term cannabis smokers find cardiovascular damage and attribute it to cannabis. Because this study utilized ingested CBD, they were able to separate the effects of smoking and the effects of the cannabinoid.

The negative effects, it turned out, were due more to the smoking than the cannabis itself.

How CBD Reduces Blood Pressure

Now, this is still a long way away from CBD being an effective treatment for cardiovascular diseases like hypertension. Serious conditions have many factors at play—lifestyle, diet, genetics, life circumstances, etc.—and taking some CBD oil isn’t necessarily going to make it all better. There are no magic pills to fix these things, despite what your friendly neighborhood pharmaceutical company would like you to believe.

While it may not be a cure for hypertension, cannabis does provide a natural, safe remedy for people to help manage their stress and blood pressure.

To minimize cardiovascular damage, you may want to consider an oral dose, through a CBD edible, tincture, or even pure CBD oil. However, if you’re set on smoking flower, reputable high CBD strains like Harlequin, Critical Mass, and Blue Shark may be helpful.

 

Source:https://haveaheartcc.com/can-cannabis-lower-blood-pressure/

CBD and Epilepsy/Seizures

 

There has been a lot of talk in the media about the use of cannabis products in the treatment of epilepsy and non-epileptic seizures. This has generated a lot of interest as well as confusion over the different forms of cannabis that are being discussed, their legality and their safety.

Medical cannabis has anticonvulsant properties. The cannabis plant contains 85 different chemical compounds called cannabinoids. The most commonly known is tetrahydrocannabinol (THC), but most of the anticonvulsant properties come from a cannabinoid called cannabidiol (CBD).Our cannabidiol products contain virtually no THC (0.3%).

The cannabidiol (CBD) has been shown to be very effective in the treatment of refractory epilepsy for some patients with Dravet and Lennox Gastaut syndromes, tuberous sclerosis and infantile spasms.

For many who have used CBD oil, the treatment has provided relief when nothing else could. About two thirds of epilepsy patients will be responsive to the first or second medicine given for epilepsy. However, once an epilepsy patient has taken two different medicines without relief, the odds that a third medication will work are less than 1 percent. That leaves other options, such as special diets, surgeries—or CBD oil!

Edibles: How Do They Work?

The primary psychoactive chemical in cannabis is THC, a cannabinoid. However, when these leaves are left raw and are un-aged, the cannabinoid found in them is THCA, which isn’t psychoactive at all. THCA only becomes THC — the stuff that gets you high — after it’s aged or, most effectively, exposed to heat. It’s a process called decarboxylation.

When looked at solely from the perspective of biochemical composition, raw cannabis leaves are excellent sources of certain vitamins, minerals and fiber. If that sounds surprising, keep in mind that even though they get you stoned, they are still green leafy plants. Raw cannabis is high in:

-Vitamin K (Essential for blood clotting) -Vitamin C (Essential for immune systems) -Iron (Essentialforbloodoxygenation) -Calcium (Essential for bones)

-Folate (Essential for DNA repair)
More specifically, cannabis is super high in fiber. So, if yourdietislacking,itcouldbethe answer.

Antioxidants are essential to our bodies because they protect us from stress and other damage, as well as against things like blood vessel disease and cancer. They’re also our body’s only defense against “free radicals,” which are highly reactive molecules that can wreak havoc on our bodies over time.

Cannabis, whether raw or cooked, is chockfull of antioxidants that our bodies need. So, whether you’re infusing weed into brownies or juicing raw leaves — you’re going to get the stuff you need.

Edibles aren’t particularly useful for sudden relief because they can take 90 minutes before they s tart having an effect, and unpredictable bouts of it. However, if you know when to anticipate them—for things like menstrual cramps, after chemotherapy, etc.—consuming marijuana is an excellent way to curb nausea, stomach pains and more.

People who ingest cannabis often experience a more intense and longer lasting full-body high than people who smoke it. You can experience a high that typically lasts one to two hours (while smoking). So, if you’re smoking medical marijuana for pain relief, cooking with it won’t just help locate and neutralize the pain you’re suffering from, but it’ll also provide more relief and for a longer duration of time.

A known fact is that you can’t really get all the benefits from smoking because it’s close to impossible to smoke a clinical level of the needed cannabinoids.However, when made into highly concentrated oils, you can get the recommended dosage in just a drop or two.

CBD and Arthritis

Cannabidiol (CBD) is not psychoactive. One of the most crucially important qualities of CBD is its lack of psycho-activity. In layperson’s terms, this means that cannabidiol wont get you high. Unlike THC, the cannabinoid with the legendary power of producing euphoric sensations, Cannabidiol CBD is inert.

  • CBD derived for the HEMP plant(male cannabis plant) is completely LEGAL, where CBD derived from the Cannabis plant (the female/bud producing plant) is currently still illegal in Canada. Technically speaking, it’s THC, the cannabinoid that gets you high, which is illicit. The rules governing hemp are quite different from the restrictions placed on cannabis. Organa possesses an active business license because all of our products contain the legal amount of THC (0.3% or less per bottle/package).

Cannabinoids, such as CBD, attach themselves to specialized receptors in the brain and immune system. Researchers found that when CBD enters the body it can attach to CB2 receptors. Scientists believe CBD affects the way that these receptors respond to the signals that they recieve, helping reduce inflammation and pain. CB2 also plays a role in your immune system, attacking the tissue in your joints. This relationship tp the immune system could explain why CBD oil works well for Arthritis. In addition, CBD’s anti-inflammatory effects could also help slow down or stop the progression of RA/OA, which causes permanent damage to your joints over time. These effects also reduce several other inflammation-related RA/OA symptoms.

  • CBD relieves inflammation and joint pain
  • CBD slows the progression of joint damage
  • Cannabis-research firm, Brightfield Group, surveyed 2,400 users. This dramatic study found widespread satisfaction with CBD among regular consumers, and even revealed that 42% of those surveyed had given up pharmaceutical drugs in favour of CBD.
  • CBD oil helped reduce inflammatory pain in rats, highlighting that cannabinoid receptors are involved in joint nociception and may be advantages for the treatment of inflammatory pain.
  • A research review published in the European Journal of Neuroscience noted that increasing evidence from preclinical studies supports the therapeutic value of cannabinoids for osteoarthritis management.
  • A study published in the European Journal of Pain found that topical CBD application had therapeutic potential for relief of arthritis pain-related inflammation and behaviours.

 

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CBD and Depression

 Depression can be a predisposed condition (something you were born with) or brought on by an unfortunate event or trauma. Regardless of the cause, the symptoms of depression are often the same: feeling sad, loss of interest or pleasure in activities, changes in appetite, trouble sleeping, loss of energy, feeling worthless, and difficulty thinking, concentrating, or making decisions. ​

​ Two of the neurotransmitters affected during depression are serotonin and dopamine. Because levels of serotonin and dopamine are affected by things like diet, exercise, mental state, and stress levels, research supports the idea that some depressed people have reduced serotonin and dopamine transmission. This is where the use of CBD products can come into play.​

​ Unlike THC, the cannabinoid associated with causing marijuana’s “high effect,” CBD has a different, more indirect interaction with these cell receptors. At the same time, CBD has the unique ability to directly interact with other cell receptors, including serotonin and dopamine receptors. Thus, when ingested, CBD influences brain activity and one byproduct is the release of serotonin and dopamine throughout the body. ​

​ Research shows that CBD oil causes receptor 5-HT1A, which releases serotonin, to fire more effectively. This increases serotonin production and stabilizes its presence in the body. ​Low levels of serotonin production can lead to depression. Using CBD oil can result in the production of more serotonin to help ease this disease.​

CBD and Tourette Syndrome

 Tourette Syndrome (TS), or simply Tourette’s, is a relatively rare neurological disorder characterized by repetitive, involuntary movements and/or vocalizations. These movements and vocalizations are called tics. It is unknown exactly how many people suffer from Tourette’s, though studies suggest one out of every 162 children have the disorder. However, it’s estimated that roughly half of the children with Tourette’s are undiagnosed.​

​ While a number of medications are prescribed to those with TS, many come with several unwanted and potentially dangerous side effects. This has driven many people to search for alternative therapies to help fight the disorder and mitigate the symptoms. One of the most popular alternative therapies that has begun showing incredibly promising potential is CBD. ​

 Numerous studies have shown CBD may have the powerful ability to reduce the frequency and severity of tics and other TS symptoms. A case study of two patients with TS conducted in 2017 and published in the August issue of International Journal of Molecular Sciences found cannabinoids provided significant relief from vocal-blocking tics and were tolerated much better than commercial pharmaceuticals.​

​ It’s thought that cannabinoids are so beneficial to neurological disorders such as TS because of the numerous ECS receptors located in the brain. Because CB1 receptors primarily are found in the brain and nervous system, cannabinoids are able to directly impact the functioning of the nervous system and help to balance it out, thereby reducing tics.​

CBD and PTSD

We all have natural Levels of anandamide,  This is the substance found naturally in your body that helps you “cope” emotionally. It relieves the effects of any stressful situation by temporarily putting you in a state of “bliss”.​

It has been determined that anandamide is at a considerably lower level in patients that are experiencing PTSD. It has also been known for a considerable amount of time that THC, which is a high percentage component of cannabis, has a built-in capacity to trigger the same receptors that are activated by anandamide.​

When experiencing PTSD, both CBD and THC can help you cope by putting you in that same “state of bliss” that is naturally created by anandamide. We can therefore safely assume that the utilization of Cannabis may be considered as a treatment against PTSD in order to deal with a shortage of anandamide.​

The consumption of CBD can have a drastic impact on the reduction of anxiety among people who are suffering from PTSD. A huge benefit of using CBD is that CBD doesn’t have any psychoactive action, so it can be used daily at work or while driving. CBD helps treat PTSD in a very different manner to THC. Indeed, PTSD patients all have far lower levels of endocannabinoids, along with higher CB1 receptor densities. Normally, the CB1 receptor deactivates any traumatic memories you may have so you basically ‘forget.’ If you have an endocannabinoid deficiency, on the other hand, you will suffer from chronic anxiety, impaired fear distinction, and other issues associated with PTSD. Cannabinoids act on the two receptors, CB1 and CB2, and helps them regain normal function.​

CBD and ADHD

    ADHD stands for Attention Deficit Hyperactivity Disorder, and is a neurodevelopmental disorder, a syndrome of the brain that affects executive functioning skills which includes important functions like attention, concentration, memory, motivation and effort, learning from mistakes, impulsivity, hyperactivity, organization and social skills to name a few. Some examples are wasting energy on things that really don’t matter, unable to complete important tasks because they are unable to focus, jumping from one shiny object to the next, increased anxiety, and overthinking things. Due to genetics, this disorder is caused by chemical and structural differences in the brain.

   Treatment for ADHD is most commonly a combination of medication and Behaviour Therapy. Behaviour Therapy can teach people coping skills and strategies, learn how to focus, and how to change or redirect their line of thinking.  Learned behaviours can overcome some of the symptoms of ADHD, and most adults can function without medication. Some of the side effects associated with ADHD medications consist of :

  • Sleeping problems
  • Decreased appetite
  • Delayed growth (children)
  • Headaches
  • Stomachaches
  • Rebound irritability when medication wears off
  • Tics
  • Moodyness
  • Irritability

 If you have ADHD, taking control of your anxiety can be a huge step towards improving your ADHD. CBD oil can boost your mental clarity and can help the way you feel on any given day. Some people have noticed after taking CBD effects from taking it happen instantaneously, they had less mental resistance, improved communication with other people and being more talkative, feelings of living in their body and not living in their head, nerves were calmed, no brain fog, feel more connected to others, important tasks were being completed as opposed to being side tracked and less irritability towards other people and themselves.

CBD and Autism

 

Many people are now familiar with the videos of children with seizure disorders being calmed and treated completely with cannabis. Similarly, we are beginning to see more and more “anecdotal evidence” that CB2 receptor is found to help the management of autism. In fact, a 2013 study at the Second University in Naples, Italy in association with the Medical School at Stanford University in California found that a malfunctioning or otherwise unhealthy endocannabinoid system may contribute to autism. 

The Autism Research Institute has described that the use of medical marijuana has had improved symptoms such as  “anxiety, aggression, panic disorder, generalized rage, tantrums, property destruction and self-injurious behaviour.” The aforementioned 2013 study in Italy by Dr. Piomelli and Dr. Manzoni has revealed critically important discoveries about the “Bliss Molecule” anandamide and how cannabis compounds like CBD and THC can be used to stimulate imbalances in the body’s endocannabinoid system and directly helping to treat autism patients in the process. They both consider Cannabis as an optimal contributor to scientific approaches to the disorder.

The endocannabinoid system is not only important in regulating healthy behavior, it is now being shown to improve dysfunctional behaviours characterized in autistic patients. Our body’s endocannabinoid system also produces oxytocin which is essential in learning and social behavior. The chaos characterized by the Autism spectrum appears to be calmed significantly by inducing natural cannabinoids to out system. According to Dr.Bernard D. Rimland from the Autism Research Institute, the research and studies all show the need to take advantage of “relatively safe drugs like marijuana.. the reports we are seeing from parents indicate that medical marijuana often works when no other treatments, drugs or non-drugs, have helped.”

 

CBD&AUTISM